BDBM50286106 CHEMBL321570::Morphinan Cyclic Imine analogue

SMILES COC12C=CC34C[C@@]1(C)[C@@H](N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1

InChI Key InChIKey=RGJHUVJQGAAZLK-KKVBBDEKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286106   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50286106(CHEMBL321570 | Morphinan Cyclic Imine analogue)
Affinity DataIC50:  2.60nMAssay Description:Compound was tested for its ability to displace [3H]-U-69,593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 10...More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50286106(CHEMBL321570 | Morphinan Cyclic Imine analogue)
Affinity DataIC50:  0.260nMAssay Description:Compound was tested for its ability to displace [3H]-U-69,593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 10...More data for this Ligand-Target Pair
In DepthDetails Article